USDAR Bio

Study Info
Started In 2021
Sites 5
Enrolled 67
USDAR BIO: Premise
USDAR Consortium sites provide the foundation for creating the largest drug allergy biorepository in the United States. Allergy specialists typically rule out or confirm drug allergies by using tests such as skin tests, patch tests, and drug challenge tests. However, knowledge of the underlying biological mechanisms of drug allergy and risk factors for drug allergy is limited. The USDAR Biorepository invites patients with confirmed drug allergies to enroll. Their samples will provide insight into the biological mechanisms and associations with true drug allergy. These samples, combined with medical and drug allergy history, will provide a holistic understanding of their drug allergy and advance drug allergy knowledge and possible biological mechanisms.
Study Goals:
Understand drug allergy
Capture individuals truly allergic to medications
To assess immunophenotypes of drug allergy
We will assess immune cell activation patterns and biomarkers to discover more about the science of drug allergy
Our Process
01
Patient Identification
Patients with acute drug reactions or those who test positive with drug allergy tests are eligible for USDAR BIO
02
Sample Collection
We collect clinical data, perform surveys, and collect samples from blood and sometimes urine and saliva from participants who consent and enroll in USDAR BIO
03
Analysis
Samples are analyzed to discover drug allergy mechanisms and associations
Participating Sites
Team Members
PI, Allergy
Site PI, Emergency Department
Site Investigator, Allergy
Site PI
Site PI
Site PI
Site Investigator